Nuclear RNA export.
نویسندگان
چکیده
RNA export is the process by which RNAs are transported to the cytoplasm after synthesis, processing, and RNP assembly within the nucleus. The primary focus of this review is mRNA export with particular attention paid to the yeast Saccharomyces cerevisiae. Because there is rather little known about mRNA export in general and even less about yeast mRNA export, our thinking about the problem is influenced by information from other transport processes. These include not only mRNA export in vertebrate systems but also studies on the export of other RNA substrates and even studies on protein import. Several of these areas of investigation have recently intersected in gratifying ways.
منابع مشابه
Jumping over the fence: RNA nuclear export revisited
Strambio-De-Castilla, Caterina, "Jumping over the fence: RNA nuclear export revisited" (2013).
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متن کاملPHAX, a Mediator of U snRNA Nuclear Export Whose Activity Is Regulated by Phosphorylation
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Our understanding of protein export from the nucleus to the cytoplasm has been advanced recently by the discovery of active, signal-mediated export pathways. Nuclear export signals have been identified in several proteins, the majority of which are RNA-binding proteins. Nuclear export of RNA molecules is likely to be driven by protein-based nuclear export signals.
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ورودعنوان ژورنال:
- Genes & development
دوره 12 21 شماره
صفحات -
تاریخ انتشار 1998